Molecular Formula | C7H14O6 |
Molar Mass | 194.18 |
Density | 1.56±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 190-198 °C |
Boling Point | 250.62°C (rough estimate) |
Specific Rotation(α) | (H2O)-80.3 |
Solubility | DMSO : 250 mg/mL (1287.47 mM; Need ultrasonic) |
Appearance | Solid |
Color | White to Off-White |
pKa | 12.98±0.70(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.572 |
MDL | MFCD00021405 |
Physical and Chemical Properties | Chemical properties of white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from seabuckthorn. |
Use | Uses for content determination/identification/pharmacological experiments and other pharmacological effects: antioxidant, anti-aging, cholesterol reduction |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
introduction | (-)-white sparrow lignin is a white crystalline powder, which has the effects of anti-oxidation, delaying aging and lowering cholesterol. |
biological activity | L-Quebrachitol (L-QCT) is a natural product that can be isolated from many plants and promotes proliferation and cell DNA synthesis. L-Quebrachitol can up-regulate bone morphogenetic protein-2 (BMP-2), runt-related transcription factor-2 (Runx2) and mitogen-activated protein kinase (MAPK) related regulatory genes and Wnt/β-catenin signaling pathway, and down-regulate mRNA levels of nuclear factor-κB(NF-κB) ligand (RANKL) receptor activator. |
target | TargetValue BMP-2 () Runx2 () MAPK () Wnt/β-catenin () NF-κB () |
Target | Value |
chemical properties | white crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from seabuckthorn. |
use | (-)-white sparrow lignin has the effects of anti-oxidation, anti-aging and cholesterol reduction. used for content determination/identification/pharmacological experiments and other pharmacological effects: anti-oxidation, anti-aging, lower cholesterol |
Introduction
(-)-white sparrow lignin is a white crystalline powder, which has the effects of anti-oxidation, delaying aging and lowering cholesterol.
biological activity
L-Quebrachitol (L-QCT) is a natural product that can be isolated from many plants and promotes proliferation and cell DNA synthesis. L-Quebrachitol can up-regulate bone morphogenetic protein-2 (BMP-2), runt-related transcription factor-2 (Runx2) and mitogen-activated protein kinase (MAPK) related regulatory genes and Wnt/β-catenin signaling pathway, and down-regulate nuclear factor-& kappa;B(NF-& kappa;B) mRNA level of ligand (RANKL) receptor activator.
Target
Target Value
BMP-2
Runx2
MAPK
Wnt/β-catenin
NF-κ B